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3,4,5-Trihydroxycinnamic acid decyl ester

CAS No. 1770778-45-4

3,4,5-Trihydroxycinnamic acid decyl ester( —— )

Catalog No. M35097 CAS No. 1770778-45-4

3,4,5-Trihydroxycinnamic acid decyl ester, an effective inhibitor of lipid absorption and accumulation, exhibits anti-obesity properties and acts as a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    3,4,5-Trihydroxycinnamic acid decyl ester
  • Note
    Research use only, not for human use.
  • Brief Description
    3,4,5-Trihydroxycinnamic acid decyl ester, an effective inhibitor of lipid absorption and accumulation, exhibits anti-obesity properties and acts as a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.
  • Description
    3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.
  • In Vitro
    3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro.3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM.3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation.
  • In Vivo
    3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally.Animal Model:6 weeks old Male ddY mice Dosage:30 mg/kg, 150 mg/kg Administration:Oral administration Result:Reduced plasma TG in a dose-dependent manner.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1770778-45-4
  • Formula Weight
    336.42
  • Molecular Formula
    C19H28O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (297.25 mM; Ultrasonic )
  • SMILES
    CCCCCCCCCCOC(=O)\C=C\c1cc(O)c(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Masahiko Imai ,et al. Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation. Bioorg Med Chem. 2015 Jul 1;23(13):3788-95.?
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